Description

5-Amino-2-Fluoro-4-Methylanisole is a high-purity, multi-functional aromatic amine derivative, serving as a critical advanced intermediate in fine chemical synthesis. Its value lies in the strategic positioning of its amino, fluoro, and methoxy functional groups, enabling precise molecular construction for complex target compounds. This product is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty dye industries seeking to develop novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity, metabolic stability, and lipophilicity.
• Dye and Pigment Manufacturing: Serves as a precursor for high-value, light-fast azo dyes and complex organic pigments, contributing to vibrant colorants for textiles, inks, and plastics.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and organic electronic materials due to its electron-donating amino group and fluorine substitution.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and process chemistry, enabling structure-activity relationship (SAR) studies and route optimization.

Basic Information

Product Name	5-Amino-2-Fluoro-4-Methylanisole
CAS No.	77153-73-2
Molecular Formula	C8H10FNO
Molecular Weight	155.17 g/mol
Synonyms	2-Fluoro-5-amino-4-methylanisole; 4-Methyl-5-amino-2-fluoroanisole; 5-Amino-2-fluoro-4-methoxytoluene; 2-Fluoro-4-methyl-5-methoxyaniline; Benzenamine, 2-fluoro-4-methyl-5-methoxy-; 5-Methoxy-2-fluoro-4-methylaniline
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Fluoro-4-Methylanisole is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for use in sensitive applications. A detailed Certificate of Analysis (COA) documenting purity, impurity profile, and physical characteristics is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.