Description

(Tyr0)-Melanocyte-Stimulating Hormone-Release Inhibiting Factor CAS NO 77133-61-0 is a synthetic peptide analog of the endogenous neuropeptide MIF-1, designed for research into neuroendocrine regulation and melanocyte activity. This compound is of significant interest for its potential role in modulating hormone release and studying related physiological pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in neuroscience, endocrinology, and dermatological research.

Application

• Neuroscience Research: Investigation of neuropeptide function, neurotransmitter interactions, and central nervous system signaling pathways.
• Endocrinology Studies: Research into the regulation of pituitary hormone secretion, including melanocyte-stimulating hormone (MSH) and related factors.
• Dermatological Research: Exploration of melanogenesis regulation, skin pigmentation disorders, and potential therapeutic targets.
• Biochemical Assay Development: Use as a reference standard or active component in in vitro and in vivo bioassays.
• Pharmaceutical R&D: Pre-clinical studies for drug discovery programs targeting neuroendocrine disorders or skin conditions.
• Academic Research: Fundamental studies in universities and research institutes on peptide structure-activity relationships (SAR).

Basic Information

Item	Details
Product Name	(Tyr0)-Melanocyte-Stimulating Hormone-Release Inhibiting Factor
CAS No.	77133-61-0
Molecular Formula	C25H35N7O6
Molecular Weight	529.59 g/mol
Synonyms	Tyr0-MIF-1; Tyr-MIF-1; L-Tyrosyl-L-prolyl-L-leucyl-glycinamide; Tyr-Pro-Leu-Gly-NH2; Melanostatin (Tyr0 analog); MSH Release-Inhibiting Factor (Tyr0-); Pro-Leu-Gly Amide (Tyr0-); PLG-NH2 (Tyr0-); Neuropeptide MIF-1 (Tyr0 analog)
EINECS	Contact for details

Quality Control

Our (Tyr0)-MIF-1 is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous quality testing protocols, and specifications can be aligned with customer requirements for specific research or development projects.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with molecular weight
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.