Description

Triprolyl Angiotensin Ii is a synthetic peptide analog of the potent vasoconstrictor hormone Angiotensin II, modified with a triprolyl sequence. This modification is crucial for enhancing its stability and specificity in biochemical research and pharmaceutical development. It is an essential tool for researchers and developers in the fields of cardiovascular pharmacology, hypertension studies, and peptide-based drug discovery.

Application

• Biochemical Research: Used as a stable reference standard and active agent in studies of the renin-angiotensin system (RAS).
• Pharmacological Studies: Critical for in vitro and in vivo assays investigating vasoconstriction, blood pressure regulation, and receptor binding (AT1/AT2).
• Drug Discovery & Development: Serves as a key intermediate or lead compound in the development of novel antihypertensive and cardiovascular therapeutic agents.
• Diagnostic Reagent Manufacturing: Employed in the production of test kits and assays for clinical research and diagnostic purposes related to cardiovascular diseases.
• Academic Research: Utilized in university and institutional labs for fundamental research on peptide hormones, signal transduction, and metabolic pathways.

Basic Information

Product Name	Triprolyl Angiotensin Ii
CAS No.	77119-79-0
Molecular Formula	C53H78N16O12
Molecular Weight	1091.3 g/mol
Synonyms	Angiotensin II, Triprolyl-; [Pro1, Pro2, Pro3]-Angiotensin II; H-Pro-Pro-Pro-Arg-Val-Tyr-Ile-His-Pro-Phe-OH; Asp-Arg-Val-Tyr-Ile-His-Pro-Phe (1-8) peptide with N-terminal triproline extension; Triprolyl-Ang II; AII Triprolyl Analog
EINECS	Contact for details

Quality Control

Our Triprolyl Angiotensin Ii is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, DMSO, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.