Description

6-Chloro-8-(1-piperazinyl)imidazo[1,2-a]pyrazine is a high-purity, heterocyclic organic compound featuring a fused imidazopyrazine core substituted with chlorine and a piperazine moiety. This specific molecular architecture makes it a critical intermediate and building block in advanced organic synthesis, particularly for the development of novel pharmacologically active molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in creating new therapeutic agents, especially within kinase inhibitor and central nervous system (CNS) drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Scaffold: Serves as a core structural element for designing and synthesizing potential kinase inhibitors for oncology and inflammatory diseases.
• CNS Drug Discovery: Used in medicinal chemistry programs targeting neurological disorders due to the privileged structure of the imidazopyrazine heterocycle.
• Chemical Biology Probe: Employed in the synthesis of tool compounds for studying biological pathways and target validation.
• Agrochemical Research: Potential intermediate for developing new crop protection agents with novel modes of action.
• Academic & Contract Research: Utilized in university and CRO settings for methodological studies and novel heterocyclic chemistry.

Basic Information

Product Name	6-Chloro-8-(1-piperazinyl)imidazo[1,2-a]pyrazine
CAS No.	77111-80-9
Molecular Formula	C10H11ClN6
Molecular Weight	250.69 g/mol
Synonyms	6-Chloro-8-piperazin-1-ylimidazo[1,2-a]pyrazine; Imidazo[1,2-a]pyrazine, 6-chloro-8-(1-piperazinyl)-; 8-Piperazin-1-yl-6-chloroimidazo[1,2-a]pyrazine; 6-Chloro-8-(piperazin-1-yl)imidazo[1,2-a]pyrazine; 77111-80-9; 6-Chloro-8-piperazinylimidazo[1,2-a]pyrazine; 6-Chloro-8-(1-piperazinyl)-imidazo[1,2-a]pyrazine
EINECS	Contact for details

Quality Control

Every batch of our 6-Chloro-8-(1-piperazinyl)imidazo[1,2-a]pyrazine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.