Description

2-Hydroxysagamicin is a chemically modified derivative of the aminoglycoside antibiotic sagamicin, characterized by the introduction of a hydroxyl group. This modification is of significant interest for its potential to alter biological activity, pharmacokinetic properties, and reduce toxicity profiles compared to the parent compound. It serves as a critical pharmaceutical intermediate and reference standard for researchers and manufacturers in the life sciences sector, particularly in antibiotic development and microbiological studies.

Application

• Pharmaceutical Intermediate: Key starting material or building block in the synthesis of novel or modified aminoglycoside antibiotics.
• Research & Development: Used as a reference standard in microbiological assays, structure-activity relationship (SAR) studies, and pharmacological research.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the production pathway for specialized antibiotic formulations.
• Biochemical Research: Tool compound for studying bacterial ribosome interaction, antibiotic resistance mechanisms, and modes of action.
• Quality Control: Serves as an analytical standard for the identification and quantification of sagamicin and related compounds in raw materials and finished products.

Basic Information

Product Name	2-Hydroxysagamicin
CAS No.	77052-96-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2-Hydroxysagamicin; Sagamicin, 2-hydroxy-; 2-Hydroxy-sagamicin; 6'-N-Methyl-2''-hydroxygentamicin C1a; Antibiotic G-52, 2-hydroxy-; 2-Hydroxy-6'-N-methylgentamicin C1a; 2''-Hydroxysagamicin; 2-Hydroxy antibiotic G-52
EINECS	Contact for details

Quality Control

Our 2-Hydroxysagamicin is produced and tested under a rigorous quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles. Our quality commitment supports applications in GMP-compliant pharmaceutical manufacturing and critical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Recommended long-term storage at controlled room temperature (15-25°C).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.