Description

Enkephalin, Alanh2(5)- CAS NO 77044-76-9 is a synthetic peptide analog of the endogenous opioid peptide enkephalin, specifically modified with an alanine substitution. This compound is of significant interest in biochemical and pharmacological research for studying opioid receptor interactions and signal transduction pathways. It serves as a critical tool for researchers and developers in the pharmaceutical, neuroscience, and life science sectors, enabling the exploration of pain management mechanisms and novel therapeutic agents.

Application

• Neuroscience Research: Used as a reference standard and active agent in studies of the endogenous opioid system, receptor binding assays, and neuronal signaling.
• Pharmacological Development: Serves as a key intermediate or lead compound in the discovery and development of new analgesic and neuroprotective drugs.
• Biochemical Assays: Employed in enzyme studies, cell-based assays, and in vitro experiments to investigate peptide metabolism and stability.
• Academic & Institutional Research: Provides a high-purity reagent for university labs and research institutes focusing on neuropeptides and their physiological roles.
• Diagnostic Tool Development: Can be utilized in the development of immunoassays and other diagnostic methods for detecting enkephalin-related biomarkers.

Basic Information

Product Name	Enkephalin, Alanh2(5)- CAS NO 77044-76-9
CAS No.	77044-76-9
Molecular Formula	C27H35N5O7
Molecular Weight	541.60 g/mol
Synonyms	[Ala2]-Leu-Enkephalin; H-Tyr-Ala-Gly-Phe-Leu-OH; Leu-Enkephalin, [Ala2]-; L-Alanine replaced leucine-enkephalin; Alanine-2-leucine enkephalin; Opioid peptide analog; YAGFL; 77044-76-9
EINECS	Contact for details

Quality Control

Our Enkephalin, Alanh2(5)- is produced under stringent conditions to ensure the highest standards of purity and consistency, suitable for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous quality testing protocols, and specifications can be tailored to meet specific research or cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.