Description

δ-n-Methylarginine is a high-purity, non-proteinogenic amino acid derivative of L-arginine, where a methyl group is substituted on the delta nitrogen of the guanidino moiety. This specific structural modification makes it a valuable biochemical tool and a critical intermediate in pharmaceutical research and development. It is primarily utilized by research institutions and industrial R&D departments focused on nitric oxide synthase (NOS) inhibition, metabolic pathway studies, and the synthesis of novel therapeutic agents. Our supply ensures consistent quality and reliable availability for your most demanding projects.

Application

• Biochemical Research: As a selective inhibitor of nitric oxide synthase (NOS) isoforms for studying NO-mediated signaling pathways.
• Pharmaceutical Intermediates: A key building block in the synthesis of novel drug candidates targeting cardiovascular and neurological disorders.
• Metabolomics & Proteomics: Used as a standard or reagent in mass spectrometry and analytical studies of arginine metabolism.
• Enzyme Kinetics: Employed in in vitro assays to investigate enzyme-substrate interactions and inhibition constants.
• Cell Culture Studies: Applied in cell-based research to modulate cellular NO production and study its downstream effects.
• Reference Standard: Serves as a high-purity certified reference material (CRM) for quality control in analytical laboratories.

Basic Information

Product Name	δ-n-Methylarginine
CAS No.	77044-73-6
Molecular Formula	C7H16N4O2
Molecular Weight	188.23 g/mol
Synonyms	Nδ-Methyl-L-arginine; L-Nδ-Methylarginine; δ-N-Mono-methyl-L-arginine; MMA; N5-Methyl-L-arginine; (S)-2-Amino-5-[(methylamino)iminomethyl]aminopentanoic acid; NG-Monomethyl-L-arginine; L-NMMA
EINECS	Contact for details

Quality Control

Our δ-n-Methylarginine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and MS, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.