Description

5-Pyrimidinecarbonitrile, 2-(4-Hydroxyphenyl)- (9Ci) is a high-purity, heterocyclic organic compound featuring a pyrimidine core substituted with a nitrile and a hydroxyphenyl group. This specialized chemical building block is critical for advanced research and development in pharmaceutical and agrochemical synthesis. It is primarily sought by R&D chemists and process development scientists for the construction of novel active molecules, particularly in the areas of kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for the development of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of advanced active ingredients for crop protection products, leveraging its heterocyclic structure.
• Chemical Synthesis Building Block: Provides a versatile scaffold for constructing complex heterocyclic compounds in medicinal and combinatorial chemistry.
• Material Science Research: Investigated as a monomer or precursor for functional organic materials and polymers with specific electronic properties.
• Academic & Industrial R&D: Employed in research laboratories for method development and exploring new chemical reactions and pathways.

Basic Information

Product Name	5-Pyrimidinecarbonitrile, 2-(4-Hydroxyphenyl)- (9Ci)
CAS No.	77017-54-0
Molecular Formula	C11H7N3O
Molecular Weight	197.19 g/mol
Synonyms	2-(4-Hydroxyphenyl)-5-pyrimidinecarbonitrile; 2-(4-Hydroxyphenyl)pyrimidine-5-carbonitrile; 4-(5-Cyanopyrimidin-2-yl)phenol; 77017-54-0; 2-(p-Hydroxyphenyl)-5-cyanopyrimidine; 5-Cyano-2-(4-hydroxyphenyl)pyrimidine
EINECS	Contact for details

Quality Control

Our production of 5-Pyrimidinecarbonitrile, 2-(4-Hydroxyphenyl)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets exacting R&D and process chemistry standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.