Description

Carnitinylmaleate-Isoluminol CAS NO 76966-72-8 is a specialized chemiluminescent reagent formed by conjugating L-carnitine with isoluminol via a maleate linker. This compound matters for its unique ability to generate a light signal in the presence of specific enzymes or reactive oxygen species, making it a critical tool for sensitive detection and quantification. It is primarily needed by researchers and manufacturers in the fields of clinical diagnostics, biochemical research, and analytical chemistry for developing advanced assay systems.

Application

• Chemiluminescence Immunoassays (CLIA): Used as a tracer or label for the detection of antigens, antibodies, hormones, and other biomarkers in clinical diagnostic kits.
• Enzyme Activity Assays: Employed as a substrate for enzymes like peroxidases and oxidases to measure enzymatic activity with high sensitivity.
• Reactive Oxygen Species (ROS) Detection: Applied in research to detect and quantify superoxide, hydrogen peroxide, and other ROS in cellular and biochemical studies.
• Biosensor Development: Integrated into sensor platforms for environmental monitoring, food safety testing, and point-of-care diagnostics.
• Pharmaceutical Research: Utilized in drug discovery and development for high-throughput screening and mechanistic studies involving oxidative pathways.
• DNA Hybridization Assays: Can be used as a non-radioactive label for the detection of specific DNA sequences.

Basic Information

Product Name	Carnitinylmaleate-Isoluminol
CAS No.	76966-72-8
Molecular Formula	C₂₀H₂₈N₄O₆
Molecular Weight	420.46 g/mol
Synonyms	L-Carnitinylmaleate Isoluminol; N-(3-Carboxy-2-hydroxypropyl)-N-(5-amino-2,3-dihydro-1,4-phthalazinedione)maleamate; Isoluminol L-carnitine ester; Carnitine-isoluminol conjugate; CLIA Reagent; Chemiluminescent Carnitine Derivative; 5-Amino-N-(3-carboxy-2-hydroxypropyl)-2,3-dihydro-1,4-phthalazinedione 4-(2-carboxyethenyl) ester
EINECS	Contact for details

Quality Control

Our Carnitinylmaleate-Isoluminol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and functional performance testing in standard chemiluminescence assays. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to ensure the material meets the stringent requirements for research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to moisture, heat, or light may lead to decomposition and reduced performance. For long-term storage, consider desiccant and under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Functional Activity	Chemiluminescence signal meets reference standard

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.