Description

Racecadotril is a potent and selective enkephalinase inhibitor, a key active pharmaceutical ingredient (API) used in the treatment of acute diarrhea. Its primary value lies in its antisecretory mechanism, which effectively reduces fluid secretion in the intestines without affecting intestinal motility. This product is essential for pharmaceutical manufacturers developing and producing antidiarrheal medications, particularly for pediatric and adult formulations. Racecadotril CAS NO 76932-19-9 is supplied under stringent quality control to ensure efficacy and safety in final drug products.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription and over-the-counter (OTC) antidiarrheal drugs.
• Pediatric Formulations: Specially formulated granules, sachets, or oral suspensions for the treatment of acute diarrhea in children.
• Adult Oral Dosage Forms: Used in the manufacture of tablets and capsules for adult gastroenterological therapy.
• Combination Drug Development: Potential for use in combination with other therapeutic agents for enhanced gastrointestinal treatment protocols.
• Veterinary Medicine: Application in veterinary pharmaceuticals for managing diarrhea in animals.
• Clinical Research: Serves as a reference standard and raw material for pharmacological studies and new drug development.

Basic Information

Product Name	Racecadotril
CAS No.	76932-19-9
Molecular Formula	C21H23NO4S
Molecular Weight	385.48 g/mol
Synonyms	Acetorphan; (3-(Acetylthio)-2-benzylpropanoyl)glycine Benzyl Ester; Tiorfan; RU-41744; N-[(R)-2-[(Acetylsulfanyl)methyl]-1-oxo-3-phenylpropyl]glycine Benzyl Ester; Racecadotrilum; Benzyl (3-(Acetylthio)-2-benzylpropanoyl)glycinate
EINECS	Contact for details

Quality Control

Our Racecadotril is manufactured and tested to meet the highest pharmaceutical standards. Quality is assured through a comprehensive battery of tests including identification, assay, impurity profiling, and residual solvent analysis. We adhere to current Good Manufacturing Practices (cGMP) and can supply material compliant with major pharmacopoeial standards (e.g., USP, EP) upon request. A detailed Certificate of Analysis (COA) is provided with each batch to guarantee purity, identity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. The container should be kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.