Description

H-Pro-Pro-Oh Hcl CAS NO 76932-06-4 is a high-purity, protected dipeptide derivative, specifically the hydrochloride salt of H-Pro-Pro-OH. This compound serves as a critical building block and intermediate in advanced organic synthesis and peptide research. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and fine chemical manufacturers for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex peptide-based drugs and protease inhibitors.
• Biochemical Research: Used as a standard or substrate in enzymatic studies and metabolic pathway investigations.
• Peptide Synthesis: An essential building block for solid-phase and solution-phase peptide synthesis, particularly for introducing proline-rich sequences.
• Chemical Biology: Employed in the development of probes and tools for studying protein-protein interactions and cell signaling.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	H-Pro-Pro-Oh Hcl
CAS No.	76932-06-4
Molecular Formula	C10H17N3O3 • HCl
Molecular Weight	263.72 g/mol
Synonyms	H-Pro-Pro-OH hydrochloride; L-Prolyl-L-proline hydrochloride; Pro-Pro dipeptide HCl; (S)-1-((S)-Pyrrolidine-2-carbonyl)pyrrolidine-2-carboxylic acid hydrochloride; Boc-Pro-Pro-OH (precursor related); Fmoc-Pro-Pro-OH (precursor related); Diproline hydrochloride; 76932-06-4
EINECS	Contact for details

Quality Control

Our H-Pro-Pro-Oh Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and heavy metals. Certificates of Analysis (COA) detailing all specifications are available upon request to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.