Description

Dazmegrel CAS NO 76894-77-4 is a synthetic chemical compound belonging to the class of thromboxane synthase inhibitors. This compound is significant for its role in biochemical research and pharmaceutical development, particularly in studies related to cardiovascular and inflammatory pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of thromboxane A2 synthase inhibitors.
• Biochemical Assays: Used as a selective inhibitor in enzymatic studies to investigate the arachidonic acid cascade and thromboxane-mediated physiological processes.
• Cardiovascular Disease Research: Employed in preclinical studies to explore mechanisms for managing conditions like thrombosis, atherosclerosis, and hypertension.
• Inflammation & Immunology Studies: Applied in research models to understand and modulate inflammatory responses linked to thromboxane production.
• Fine Chemical Synthesis: Acts as a crucial building block for the synthesis of more complex, target-specific molecules in medicinal chemistry.
• Academic Research: Utilized in university and institutional labs for pharmacological education and advanced life science research projects.

Basic Information

Product Name	Dazmegrel
CAS No.	76894-77-4
Molecular Formula	C13H12N2O3
Molecular Weight	244.25 g/mol
Synonyms	Dazmegrel; Dazmegrelum; (E)-3-[p-(1H-Imidazol-1-ylmethyl)phenyl]-2-propenoic acid; 4-[(1H-Imidazol-1-yl)methyl]cinnamic acid; UK-38,485; CGS-12970; 1-[(E)-3-(4-Imidazol-1-ylmethylphenyl)prop-2-enoyl]imidazole; UK 38485
EINECS	Contact for details

Quality Control

Our Dazmegrel is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including identity confirmation by spectroscopic methods (IR, NMR) and purity determination by HPLC, to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data and impurity profiles are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.