Description

2,4-Dichloro-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidine CAS NO 76872-28-1 is a high-value, heterocyclic organic compound featuring a fused thienopyrimidine and cyclopentane ring system. This specialized intermediate is critical for the synthesis of complex molecules, offering a versatile scaffold for medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Acts as a precursor in the research and synthesis of novel herbicides or fungicides with specific modes of action.
• Material Science Research: Investigated for the development of organic electronic materials due to its fused heterocyclic structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	2,4-Dichloro-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidine
CAS No.	76872-28-1
Molecular Formula	C9H6Cl2N2S
Molecular Weight	245.13 g/mol
Synonyms	2,4-Dichloro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidine; 2,4-Dichloro-6,7-dihydrocyclopentathienopyrimidine; 5H-Cyclopenta[4,5]thieno[2,3-d]pyrimidine, 2,4-dichloro-6,7-dihydro-; Thieno[2,3-d]pyrimidine, 2,4-dichloro-6,7-dihydro-5H-cyclopenta[4,5]-; 76872-28-1; Cyclopentathienopyrimidine dichloro derivative
EINECS	Contact for details

Quality Control

Our production of 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP-compliant manufacturing for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 98.0% / ≥ 99.0% (High Purity Grades Available)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.