Description

L-Pyroglutamyl-L-Histidyl-3,3-Dimethylprolinamide CAS NO 76820-40-1 is a synthetic peptide derivative with a unique cyclic structure. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential role as a specialized intermediate or active pharmaceutical ingredient (API). It is primarily sought by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex peptide-based drugs and novel therapeutic candidates.
• Biochemical Research: Used as a reference standard or tool compound in proteomics, enzymology, and receptor-ligand interaction studies.
• Peptide Synthesis: Acts as a specialized precursor for solid-phase or solution-phase peptide synthesis to create custom sequences.
• Drug Discovery & Development: Investigated for potential biological activity in high-throughput screening and lead optimization programs.
• Cosmeceutical R&D: Explored for potential applications in advanced skincare formulations targeting specific biological pathways.

Basic Information

Product Name	L-Pyroglutamyl-L-Histidyl-3,3-Dimethylprolinamide
CAS No.	76820-40-1
Molecular Formula	C19H28N6O4
Molecular Weight	404.47 g/mol
Synonyms	L-Pyroglutamyl-L-histidyl-3,3-dimethylprolinamide; Pyr-His-Dmp-NH2; 5-Oxo-L-prolyl-L-histidyl-3,3-dimethyl-L-prolinamide; (S)-1-((S)-2-(1H-Imidazol-4-yl)acetamido)-3,3-dimethylpyrrolidine-2-carboxamide; GLP-1 related peptide fragment; Peptide GH-DMP; 76820-40-1
EINECS	Contact for details

Quality Control

Our L-Pyroglutamyl-L-Histidyl-3,3-Dimethylprolinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation to ensure it meets rigorous research-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.