Description

2-Chloro-n-Methyl-6,7-Dihydro-5H-Cyclopenta[D]Pyrimidin-4-Amine(Saltdata: Free) CAS NO 76780-98-8 is a high-purity, advanced pharmaceutical intermediate belonging to the cyclopentapyrimidine class of heterocyclic compounds. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its precise molecular structure and reactivity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of targeted small-molecule drugs.
• Oncology Research: Serves as a core scaffold for developing kinase inhibitors and other anticancer compounds.
• Antiviral Drug Development: Used in research programs aimed at creating novel antiviral medications.
• Chemical Biology: Employed as a probe or building block in studying biological pathways and protein interactions.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and pilot-scale manufacturing of APIs.
• Contract Research & Development (CRO/CMO): Essential raw material for organizations providing custom synthesis and development services.

Basic Information

Product Name	2-Chloro-n-Methyl-6,7-Dihydro-5H-Cyclopenta[D]Pyrimidin-4-Amine(Saltdata: Free)
CAS No.	76780-98-8
Molecular Formula	C8H10ClN3
Molecular Weight	183.64 g/mol
Synonyms	2-Chloro-N-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine; 4-Amino-2-chloro-N-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine; 2-Chloro-4-(methylamino)-6,7-dihydro-5H-cyclopenta[d]pyrimidine; 76780-98-8; Free base of 2-Chloro-N-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-Methyl-6,7-Dihydro-5H-Cyclopenta[D]Pyrimidin-4-Amine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.