Description

2-Chloro-5H,6H,7H-Cyclopenta[D]Pyrimidin-4-Amine is a versatile and high-value heterocyclic building block, specifically a chlorinated cyclopentapyrimidine derivative. This compound is critical for advanced organic synthesis, enabling the development of novel molecular architectures with targeted biological activity. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical discovery, and materials science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive pyrimidine core.
• Chemical Biology Probe Synthesis: Employed to create tool compounds for studying biological pathways and target validation.
• Material Science: Acts as a building block for organic electronic materials and specialty polymers.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Utilized in university and institutional labs for novel heterocyclic chemistry methodologies and discovery projects.

Basic Information

Product Name	2-Chloro-5H,6H,7H-Cyclopenta[D]Pyrimidin-4-Amine
CAS No.	76780-97-7
Molecular Formula	C7H8ClN3
Molecular Weight	169.61 g/mol
Synonyms	2-Chloro-4-amino-5,6,7,8-tetrahydrocyclopenta[d]pyrimidine; 4-Amino-2-chloro-5,6,7,8-tetrahydrocyclopenta[d]pyrimidine; 2-Chloro-4-aminocyclopentapyrimidine; 2-Chloro-4-amino-5,6,7,8-tetrahydro-cyclopenta[4,5]pyrimidine; 2-Chloro-5,6,7,8-tetrahydrocyclopenta[d]pyrimidin-4-amine; 76780-97-7; 2-Chloro-4-aminocyclopenta[d]pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-5H,6H,7H-Cyclopenta[D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.