Description

2-(S-Glutathionyl)Hydroquinone is a specialized biochemical conjugate formed from hydroquinone and the tripeptide glutathione. This compound is of significant interest in biochemical and toxicological research due to its role as a metabolite and potential biomarker in studies of chemical toxicity and oxidative stress pathways. It is primarily utilized by research institutions and pharmaceutical development laboratories investigating quinone metabolism, redox cycling, and cellular defense mechanisms against electrophilic species. The product is supplied with a high level of purity and batch-to-batch consistency to ensure reliable experimental results.

Application

• Biochemical Research: Used as a reference standard or reagent in studies of quinone metabolism and detoxification pathways.
• Toxicology Studies: Employed to investigate the formation and effects of reactive electrophilic metabolites in cellular systems.
• Oxidative Stress Research: Serves as a tool to study glutathione-dependent conjugation reactions and redox biology.
• Analytical Method Development: Used as a standard for developing and validating analytical methods (e.g., HPLC, LC-MS) for detecting glutathione conjugates.
• Pharmaceutical R&D: Applied in early-stage drug development to understand potential metabolic pathways and reactive intermediate formation of drug candidates.
• Enzymology Studies: Utilized as a substrate or product in assays for enzymes like glutathione S-transferases (GSTs).

Basic Information

Product Name	2-(S-Glutathionyl)Hydroquinone
CAS No.	76726-99-3
Molecular Formula	C16H21N3O8S
Molecular Weight	415.42 g/mol
Synonyms	2-(S-Glutathionyl)hydroquinone; Glutathionylhydroquinone; Hydroquinone-glutathione conjugate; 2-(Glutathion-S-yl)hydroquinone; 1,4-Benzenediol, 2-(glutathion-S-yl)-; GS-HQ; Glutathione-hydroquinone adduct; 2-(γ-Glutamylcysteinylglycyl)hydroquinone
EINECS	Contact for details

Quality Control

Every batch of 2-(S-Glutathionyl)Hydroquinone is manufactured and tested under strict quality management protocols to ensure high purity and identity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for purity, identity confirmation, and impurity profiles. We support research and development with reliable, consistent material suitable for advanced analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or Certificate of Analysis. Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere for long-term stability. Keep the container tightly sealed in a dry, cool, and well-ventilated place. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.