Description

Lhrh, n-Ac-Gly(1)-(4-Cl-Phe)(2)-Trp(3,6)- CAS NO 76712-83-9 is a synthetic peptide analog, specifically a modified fragment of Luteinizing Hormone-Releasing Hormone (LHRH). This compound is a critical research tool and a key intermediate in the development of targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D departments, biotechnology companies, and academic research institutions focused on endocrinology, oncology, and peptide chemistry.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of novel LHRH analogs and antagonists for therapeutic applications.
• Endocrinology Studies: Used in biochemical research to study hormone-receptor interactions, signal transduction pathways, and the regulation of the hypothalamic-pituitary-gonadal axis.
• Oncology Research: Investigated for its potential role in developing targeted therapies for hormone-dependent cancers, such as prostate and breast cancer.
• Peptide Chemistry & Process Development: Employed as a building block in solid-phase peptide synthesis (SPPS) and for optimizing large-scale peptide manufacturing processes.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in peptide production and regulatory submissions.
• Bioconjugation & Drug Delivery Systems: Acts as a targeting ligand or a model peptide in the development of advanced drug delivery platforms.

Basic Information

Item	Detail
Product Name	Lhrh, n-Ac-Gly(1)-(4-Cl-Phe)(2)-Trp(3,6)- CAS NO 76712-83-9
CAS No.	76712-83-9
Molecular Formula	C58H74ClN15O11
Molecular Weight	1184.74 g/mol
Synonyms	Ac-Gly-(4-Cl-D-Phe)1-D-Trp3,6-LHRH; LHRH Fragment (1-9) analog; Luteinizing Hormone-Releasing Hormone Analog; n-Acetyl-Glycyl-[4-chloro-D-phenylalanyl]-D-tryptophyl-LHRH; GnRH Analog; Gonadorelin Analog; [Ac-Gly1, 4-Cl-D-Phe2, D-Trp3,6]-LHRH; Peptide LHRH Antagonist Intermediate
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch of Lhrh, n-Ac-Gly(1)-(4-Cl-Phe)(2)-Trp(3,6)- CAS NO 76712-83-9 undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.