Description

Cyclo(Prolylsarcosyl)4 CAS NO 76710-73-1 is a synthetic cyclic tetrapeptide composed of alternating proline and sarcosine (N-methylglycine) residues. This unique structure makes it a valuable scaffold in advanced pharmaceutical research and peptide chemistry. It is primarily utilized by R&D scientists and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and studying peptide conformation and stability.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of more complex peptide-based drugs and prodrugs.
• Conformational Studies: Used as a model compound in biochemical research to investigate the relationship between cyclic peptide structure and biological activity.
• Drug Discovery Scaffold: Provides a constrained, stable framework for medicinal chemists to attach various pharmacophores in the search for new bioactive molecules.
• Biochemical Tool Compound: Employed in enzymatic assays and receptor binding studies to probe specific biological pathways.
• Cosmetic Peptide Research: Investigated for potential applications in advanced skincare formulations targeting specific skin functions.
• Academic & Industrial R&D: A critical reagent for universities and corporate labs focused on peptide synthesis methodology and novel material development.

Basic Information

Product Name	Cyclo(Prolylsarcosyl)4
CAS No.	76710-73-1
Molecular Formula	C24H36N8O8
Molecular Weight	564.60 g/mol
Synonyms	Cyclo(-Pro-Sar-)4; Cyclo(Pro-Sar)4; Cyclo(L-Prolyl-N-methylglycyl)4; Cyclic (Proline-Sarcosine) Tetramer; 1,4,7,10-Tetraazacyclododecane-2,5,8,11-tetraone derivative; Cyclotetrapeptide (Pro-Sar)4; Alternating Proline-Sarcosine Cyclic Tetrapeptide; CAS 76710-73-1
EINECS	Contact for details

Quality Control

Our Cyclo(Prolylsarcosyl)4 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and NMR for structural verification. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Specifications can be tailored to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive) and light-sensitive; desiccants are recommended for long-term storage. Keep container sealed under an inert atmosphere when not in use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.