Description

Insulin, (2-Nitro-Azidophenylacetyl)(B1)- CAS NO 76688-24-9 is a chemically modified insulin derivative, specifically designed for advanced research and development applications. This compound is critical for studies in biochemistry and pharmacology, particularly in the investigation of insulin signaling pathways and receptor interactions. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in metabolic disorder research and novel therapeutic agent development.

Application

• Biochemical Research: A key reagent for studying insulin receptor binding, activation mechanisms, and downstream signaling cascades.
• Pharmaceutical Development: Used in the design and screening of novel insulin analogs and diabetes therapeutics.
• Proteomics & Labeling Studies: The azido and nitro functional groups enable its use in photoaffinity labeling and chemical biology applications to map protein interactions.
• Metabolic Pathway Analysis: Serves as a tool compound in cellular and molecular assays to understand glucose metabolism and insulin action.
• Academic Research: Employed in university laboratories for fundamental research into endocrinology and hormone action.

Basic Information

Product Name	Insulin, (2-Nitro-Azidophenylacetyl)(B1)- CAS NO 76688-24-9
CAS No.	76688-24-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NαB1-(2-Nitro-4-azidophenylacetyl)insulin; 2-Nitro-4-azidophenylacetyl-insulin; Insulin, NαB1-(2-nitro-4-azidobenzoyl)-; Photoaffinity Labeled Insulin Derivative; Azidophenylacetyl Insulin; NAPA-Insulin; Insulin Chemical Probe
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. For this research-grade biochemical, quality is assured through stringent analytical controls including HPLC purity analysis and mass spectrometry (MS) confirmation to verify structural integrity and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep desiccated and under inert atmosphere if possible. Allow to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Biological Activity	Assessed by receptor binding assay
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.