Description

Leucinostatin B CAS NO 76663-52-0 is a potent, non-ribosomal peptide antibiotic belonging to the peptaibol family, characterized by a high content of the amino acid leucine. This compound is valued for its significant biological activity, particularly as a strong antifungal and antiviral agent, making it a critical component in advanced life science research and development. It is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic agents and biocontrol solutions.

Application

• Pharmaceutical Research: As a lead compound for developing new antifungal and antiviral drugs due to its potent membrane-disrupting activity.
• Agricultural Chemistry: Investigation as a natural biocontrol agent for protecting crops against fungal pathogens.
• Biochemical Studies: Used as a tool compound to study ion channel formation and membrane permeability in cell biology.
• Microbiology & Antibiotic Discovery: Serves as a reference standard in screening programs and mechanism-of-action studies for novel antibiotics.
• Academic Research: Fundamental studies on non-ribosomal peptide synthesis, structure-activity relationships (SAR), and peptide-lipid interactions.

Basic Information

Product Name	Leucinostatin B
CAS No.	76663-52-0
Molecular Formula	C₆₆H₁₁₃N₁₅O₁₅
Molecular Weight	1380.7 g/mol
Synonyms	Leucinostatin B; Antibiotic 1668B; Peptaibol 1668B; Leucinostatin; Leucinostatin B from Trichoderma viride; [Ile7]-Leucinostatin B; (3S,6S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,42S,45S)-3-[(2S)-Butan-2-yl]-6,9,12,15,18,21,24,27,30,33,36,39,42,45-tetradecamethyl-48-[(2S)-1-oxobutan-2-yl]-1,4,7,10,13,16,19,22,25,28,31,34,37,40,43,46-hexadecaoxo-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47-hexadecazapentacontan-50-oic acid
EINECS	Contact for details

Quality Control

Our Leucinostatin B is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and MS/NMR for structural confirmation. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to reach room temperature before opening to prevent condensation and moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.