Description

2'-n-Formylsisomycin is a chemically modified derivative of the aminoglycoside antibiotic sisomycin, identified by CAS No. 76647-54-6. This compound is a key intermediate in pharmaceutical research and development, particularly valued for its role in synthesizing novel antibiotic analogs and studying structure-activity relationships. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing new antimicrobial agents and advanced pharmaceutical intermediates.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel aminoglycoside antibiotic derivatives.
• Antimicrobial Research: Used in biochemical and microbiological research to investigate mechanisms of action and resistance.
• Structure-Activity Relationship (SAR) Studies: Essential for modifying the sisomycin core structure to enhance potency, reduce toxicity, or alter spectrum of activity.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Medicinal Chemistry: A key starting material for the discovery and optimization of new therapeutic agents targeting bacterial infections.

Basic Information

Product Name	2'-n-Formylsisomycin
CAS No.	76647-54-6
Molecular Formula	C20H39N5O8
Molecular Weight	477.56 g/mol
Synonyms	2'-N-Formylsisomycin; 2'-Deoxy-2'-(N-formyl)sisomycin; Formylsisomycin; Sisomycin, 2'-N-formyl-; 5-Deoxy-2-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-3-C-formyl-1-N-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl]-2-deoxy-D-streptamine
EINECS	Contact for details

Quality Control

Our 2'-n-Formylsisomycin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and determination of residual solvents to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.