Description

2,2'Anhydro-1-(β-Arabinofuranosyl)Orotic Acid Hydrazide is a specialized nucleoside analogue derivative with significant potential in pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate in the creation of novel antiviral and anticancer agents, particularly those targeting nucleic acid synthesis. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on nucleoside chemistry and prodrug development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of experimental antiviral and antineoplastic (anticancer) nucleoside analogues.
• Biochemical Research: Used in studies investigating enzyme inhibition, particularly targeting viral polymerases or enzymes involved in nucleotide metabolism.
• Prodrug Development: Acts as a precursor molecule for designing prodrugs aimed at improving the bioavailability and targeted delivery of active pharmaceutical ingredients (APIs).
• Antiviral Agent Synthesis: A key starting material in the research and development pipeline for potential treatments against DNA and RNA viruses.
• Chemical Biology Probes: Utilized in the development of molecular probes to study cellular processes and drug-target interactions.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for high-value, low-volume specialty chemicals.

Basic Information

Item	Details
Product Name	2,2'Anhydro-1-(β-Arabinofuranosyl)Orotic Acid Hydrazide
CAS No.	76580-72-8
Molecular Formula	C10H12N4O6
Molecular Weight	284.23 g/mol
Synonyms	2,2'-Anhydro-1-β-D-arabinofuranosylorotic Acid Hydrazide; 1-(2,3-Di-O-acetyl-β-D-arabinofuranosyl)orotic Acid Hydrazide (precursor related); Ara-Orotic Acid Hydrazide; Anhydroarabinofuranosyl Orotate Hydrazide; Nucleoside Orotate Derivative; Research Grade 76580-72-8; CAS 76580-72-8
EINECS	Contact for details

Quality Control

Every batch of 2,2'Anhydro-1-(β-Arabinofuranosyl)Orotic Acid Hydrazide is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC purity data, to ensure the material meets the exacting standards required for research and pharmaceutical intermediate applications. Our quality protocols are designed to support compliance with cGMP and ICH guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere such as nitrogen or argon for long-term storage to maintain stability and purity. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.