Description

4-(2,2,2-Trifluoroethoxy)Benzaldehyde is a high-purity fluorinated aromatic aldehyde building block, essential for introducing the trifluoroethoxy phenyl moiety into complex molecular architectures. This compound is valued for its role in modulating the physicochemical properties of target molecules, such as lipophilicity and metabolic stability. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing kinase inhibitors, CNS agents, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the trifluoroethoxy group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and stability.
• Organic Synthesis & Catalysis: A versatile reagent for palladium-catalyzed cross-coupling reactions, nucleophilic additions, and reductive aminations in complex molecule construction.
• Polymer & Resin Modifier: Incorporated into polymer backbones to alter thermal properties, chemical resistance, and surface characteristics of high-performance materials.
• Chemical Research & Development: Fundamental reagent for medicinal chemistry programs and discovery research exploring structure-activity relationships (SAR).

Basic Information

Product Name	4-(2,2,2-Trifluoroethoxy)Benzaldehyde
CAS No.	76579-46-9
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	p-(Trifluoroethoxy)benzaldehyde; 4-(Trifluoroethoxy)benzaldehyde; Benzaldehyde, 4-(2,2,2-trifluoroethoxy)-; 1-Trifluoroethoxy-4-formylbenzene; α,α,α-Trifluoro-p-ethoxybenzaldehyde; 4-Formylphenyl 2,2,2-trifluoroethyl ether; 4-(2,2,2-Trifluoroethoxy)benzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-(2,2,2-Trifluoroethoxy)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider under an inert atmosphere (nitrogen or argon) to maintain optimal purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.