Description

Flosequinan is a synthetic organic compound with significant pharmacological activity, primarily known for its role as a vasodilator. This high-purity active pharmaceutical ingredient (API) is critical for research and development in cardiovascular therapeutics. It is essential for pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions focused on developing treatments for heart failure and hypertension.

Application

• Pharmaceutical API: Serves as the active ingredient in the formulation of cardiovascular drugs for clinical research and development.
• Biochemical Research: Used as a reference standard and tool compound in pharmacological studies to investigate vasodilation mechanisms and phosphodiesterase inhibition.
• Preclinical Development: Employed in animal model studies to evaluate efficacy, pharmacokinetics, and safety profiles for potential new drug candidates.
• Analytical Standard: Utilized as a high-purity calibrant in quality control laboratories for method development and validation (HPLC, LC-MS).
• Chemical Intermediate: Can be used in the synthesis of more complex molecules or derivatives for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Flosequinan
CAS No.	76568-02-0
Molecular Formula	C17H12FNO3
Molecular Weight	297.28 g/mol
Synonyms	7-Fluoro-1-methyl-3-(methylsulfinyl)-4-quinolone; BTS 49465; Flosequinan [USAN]; Flosequinanum [Latin]; (+-)-Flosequinan; (±)-Flosequinan; 4(1H)-Quinolinone, 7-fluoro-1-methyl-3-(methylsulfinyl)-; 7-Fluoro-1-methyl-3-methylsulfinylquinolin-4(1H)-one
EINECS	Contact for details

Quality Control

Our Flosequinan is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and mass spectrometry. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.