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4-Aminobenzoyl-Poly-γ-Glutamate CAS NO 76567-21-0


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CAS No.:76567-21-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Aminobenzoyl-Poly-γ-Glutamate is a specialized functionalized polymer derivative of polyglutamic acid, designed for advanced material and biomedical applications. This compound matters for its unique combination of a photoactive aminobenzoyl moiety with the biocompatible and biodegradable poly-γ-glutamate backbone, enabling precise conjugation and modification. It is primarily needed by researchers and manufacturers in the pharmaceutical, cosmetic, and biomaterials industries for developing targeted drug delivery systems, advanced skincare formulations, and novel biodegradable polymers.

Application

  • Drug Delivery Systems: As a functional carrier for the targeted delivery of therapeutic agents, leveraging its biodegradable and modifiable structure.
  • Biomedical Research: A key intermediate in the synthesis of novel bioconjugates, probes, and biomaterials for tissue engineering and regenerative medicine.
  • Cosmetic & Skincare Formulations: Used in advanced anti-aging and moisturizing products for its film-forming and skin-adhesive properties.
  • Polymer & Material Science: Serves as a building block for creating smart, responsive hydrogels and functional coatings with specific surface properties.
  • Diagnostic Agent Development: Employed in the conjugation of imaging agents or dyes for in vitro and in vivo diagnostic applications.
  • Enzyme & Protein Immobilization: Provides a stable, functional matrix for immobilizing enzymes or proteins in biosensor and biocatalyst development.

Basic Information

Product Name 4-Aminobenzoyl-Poly-γ-Glutamate
CAS No. 76567-21-0
Molecular Formula (C5H7NO3)n•C7H6NO2 (Representative)
Molecular Weight Variable (Polymer)
Synonyms p-Aminobenzoyl Poly-γ-glutamate; 4-ABA-PGA; PGA-4-aminobenzoate; Poly(γ-glutamic acid) 4-aminobenzoic acid conjugate; Aminobenzoyl Polyglutamic Acid; 4-Aminobenzoyl-PGA; ABZ-Polyglutamate; Functionalized Poly-γ-glutamic Acid
EINECS Contact for details

Quality Control

Our 4-Aminobenzoyl-Poly-γ-Glutamate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing key parameters such as degree of substitution, molecular weight distribution, and impurity profiles are available upon request. We adhere to cGMP principles for pharmaceutical-grade material where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term stability, consider storage under an inert atmosphere such as nitrogen or argon.

Specification

Item Specification
Appearance Off-white to light yellow powder or solid
Identification (IR) Conforms to structure
Assay (Functional Group) ≥ 90% (by titration/NMR)
Degree of Substitution (DS) To customer specification
Molecular Weight (Avg.) To customer specification (e.g., 10k-500k Da)
Loss on Drying ≤ 5.0 %
Residual Solvents (GC) Meets ICH guidelines
Heavy Metals (as Pb) ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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