Description

Met-Enkephalin-Arg-Arg CAS NO 76496-10-1 is a bioactive peptide fragment derived from the endogenous opioid peptide, proenkephalin A. This compound is of significant value in biochemical and pharmacological research for studying opioid receptor interactions and signal transduction pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on neuroscience, pain management, and peptide-based therapeutic development.

Application

• Neuroscience Research: Used as a reference standard and tool compound for investigating the function and modulation of delta and mu opioid receptors.
• Biochemical Assay Development: Serves as a critical substrate or ligand in the development of high-throughput screening (HTS) assays for drug discovery targeting the opioid system.
• Pharmacological Studies: Employed in vitro and in vivo studies to understand the metabolic pathways of enkephalins and the role of extended peptide sequences.
• Diagnostic Reagent Manufacturing: Acts as a key component in the production of immunoassay kits and other diagnostic tools for measuring enkephalin-related biomarkers.
• Peptide Chemistry & Synthesis: Used as an intermediate or a model compound in solid-phase peptide synthesis (SPPS) research and process optimization.
• Academic Research: Fundamental research tool in university laboratories for studies related to neuropeptides, pain mechanisms, and cellular communication.

Basic Information

Product Name	Met-Enkephalin-Arg-Arg
CAS No.	76496-10-1
Molecular Formula	C32H52N12O8S
Molecular Weight	764.91 g/mol
Synonyms	Methionine Enkephalin-Arg-Arg; [Met5]-Enkephalin-Arg-Arg; Tyr-Gly-Gly-Phe-Met-Arg-Arg; YGGFMRR; Met-Enkephalin, Arg-Arg extended form; Opioid peptide ME-RR; Proenkephalin A (209-216); H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-OH
EINECS	Contact for details

Quality Control

Our Met-Enkephalin-Arg-Arg is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and MS for identity confirmation, to ensure compliance with high-purity research-grade standards. Comprehensive Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.