Description

Somatostatin-25 is a synthetic peptide analog of the endogenous hormone somatostatin, identified by CAS NO 76461-17-1. This compound is valued for its potent inhibitory effects on the secretion of growth hormone, insulin, and glucagon, making it a critical tool in endocrine research and therapeutic development. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on metabolic disorders and neuroendocrine research.

Application

• Endocrine Research: Used as a reference standard and active agent in studies investigating the regulation of growth hormone, insulin, and glucagon secretion.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the development of novel therapeutics for acromegaly and severe diarrhea associated with metastatic carcinoid tumors.
• Biochemical Assays: Employed in receptor binding studies, radioimmunoassays (RIA), and enzyme-linked immunosorbent assays (ELISA) to study somatostatin receptor activity.
• Metabolic Disorder Studies: Applied in preclinical research models for diabetes and other metabolic syndromes to understand hormonal pathway modulation.
• Neuroscience Research: Utilized in neuroendocrine research to investigate the role of somatostatin in the central nervous system.

Basic Information

Product Name	Somatostatin-25
CAS No.	76461-17-1
Molecular Formula	C₁₄₀H₂₂₀N₄₂O₄₃S₄
Molecular Weight	3147.6 g/mol
Synonyms	Somatostatin 25; Somatostatin-25 Peptide; SRIF-25; Growth Hormone Release-Inhibiting Hormone (25 AA); H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bridge); BIM-23025; Cyclic Somatostatin Tetradecapeptide Analog; Somatostatin (1-14) cyclic analog
EINECS	Contact for details

Quality Control

Our Somatostatin-25 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and tests for residual solvents and endotoxins where applicable. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 2.0%
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.