Description

H-Ala-Pro-NH2 HCl is a high-purity, protected dipeptide building block used in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular control in the development of complex bioactive molecules. It is primarily utilized in the pharmaceutical and biotechnology sectors for peptide synthesis, medicinal chemistry research, and as a key intermediate in the production of peptide-based therapeutics and diagnostic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block for the controlled assembly of longer, complex peptide sequences in drug discovery.
• Medicinal Chemistry & Drug Development: Serves as a crucial intermediate for structure-activity relationship (SAR) studies and the creation of novel therapeutic candidates.
• Bioconjugation & Peptide Labeling: Used in the site-specific modification of peptides for creating targeted imaging probes or drug conjugates.
• Enzyme Substrate & Inhibitor Design: Employed in the research and development of specific enzyme substrates or inhibitors, particularly for proteases.
• Chemical Biology Research: A valuable tool for probing biological processes and protein-protein interactions.
• GMP-grade Pharmaceutical Manufacturing: Suitable for use as a starting material or intermediate in the cGMP production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	H-Ala-Pro-NH2 HCl
CAS No.	76399-73-0
Molecular Formula	C8H15N3O2 • HCl
Molecular Weight	221.68 g/mol (free base: 185.22)
Synonyms	L-Alanyl-L-prolinamide hydrochloride; Ala-Pro-NH2•HCl; H-Ala-Pro-NH2 hydrochloride; Alanine-Proline amide hydrochloride; AP-NH2 HCl; L-Ala-L-Pro-NH2 HCl; N-(L-Alanyl)-L-prolinamide hydrochloride; 2-[(2S)-1-Amino-1-oxopropan-2-yl]amino]-1-(pyrrolidin-2-yl)ethanone hydrochloride
EINECS	Contact for details

Quality Control

Our H-Ala-Pro-NH2 HCl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets stringent specifications for research and pharmaceutical use. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.