Description

Ethyl 8-Benzyl-5-Hydroxy-7-Oxo-2-Phenyl-7,8-Dihydropyrido[2,3-D]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the dihydropyridopyrimidine class of heterocyclic compounds. This compound matters as a critical building block for the research and development of novel therapeutic agents, particularly in oncology and other disease areas. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting kinase inhibition.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.
• Academic Research: Employed in universities and research institutes for studying heterocyclic chemistry and developing new synthetic methodologies.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial compounds for client-specific research needs.

Basic Information

Product Name	Ethyl 8-Benzyl-5-Hydroxy-7-Oxo-2-Phenyl-7,8-Dihydropyrido[2,3-D]Pyrimidine-6-Carboxylate
CAS No.	76377-80-5
Molecular Formula	C25H21N3O4
Molecular Weight	427.45 g/mol
Synonyms	Ethyl 8-benzyl-5-hydroxy-7-oxo-2-phenyl-7,8-dihydro-5H-pyrido[2,3-d]pyrimidine-6-carboxylate; 8-Benzyl-5-hydroxy-7-oxo-2-phenyl-7,8-dihydro-5H-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester; 5H-Pyrido[2,3-d]pyrimidine-6-carboxylic acid, 7,8-dihydro-8-(phenylmethyl)-5-hydroxy-7-oxo-2-phenyl-, ethyl ester; Ethyl 8-benzyl-5-hydroxy-7-oxo-2-phenyl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 8-Benzyl-5-Hydroxy-7-Oxo-2-Phenyl-7,8-Dihydropyrido[2,3-D]Pyrimidine-6-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.