Description

Ethyl 5-Hydroxy-7-Oxo-2-Phenyl-8-Propyl-7,8-Dihydropyrido[2,3-D]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the dihydropyridopyrimidine class of heterocyclic compounds. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting specific enzymatic pathways.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of new chemical entities (NCEs) within the pyridopyrimidine scaffold.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in multi-step synthetic routes for the production of potential therapeutic agents.
• Biochemical Research: Utilized as a reference standard or inhibitor in biochemical assays to study biological mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	Ethyl 5-Hydroxy-7-Oxo-2-Phenyl-8-Propyl-7,8-Dihydropyrido[2,3-D]Pyrimidine-6-Carboxylate
CAS No.	76377-79-2
Molecular Formula	C21H21N3O4
Molecular Weight	379.41 g/mol
Synonyms	Ethyl 5-hydroxy-7-oxo-2-phenyl-8-propyl-7,8-dihydro-6H-pyrido[2,3-d]pyrimidine-6-carboxylate; 7,8-Dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid, 5-hydroxy-7-oxo-2-phenyl-8-propyl-, ethyl ester; 76377-79-2; Ethyl 5-hydroxy-7-oxo-2-phenyl-8-propyl-7,8-dihydro-6H-pyrido[2,3-d]pyrimidine-6-carboxylate; 6H-Pyrido[2,3-d]pyrimidine-6-carboxylic acid, 7,8-dihydro-5-hydroxy-7-oxo-2-phenyl-8-propyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Hydroxy-7-Oxo-2-Phenyl-8-Propyl-7,8-Dihydropyrido[2,3-D]Pyrimidine-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive compound.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.