Description

Ethyl 8-Allyl-5-Hydroxy-2-(Methylthio)-7-Oxo-7,8-Dihydropyrido[2,3-D]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development pipelines. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Serves as a core scaffold for the development of new chemical entities (NCEs) in drug discovery, especially for kinase inhibitors or other targeted therapies.
• Fine Chemical Synthesis: Used in multi-step organic synthesis to construct sophisticated pyridopyrimidine-based structures for various high-value applications.
• Biochemical Tool Compound: Potential use in biochemical assays as a reference standard or probe to study biological mechanisms.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials or niche APIs.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	Ethyl 8-Allyl-5-Hydroxy-2-(Methylthio)-7-Oxo-7,8-Dihydropyrido[2,3-D]Pyrimidine-6-Carboxylate
CAS No.	76360-94-6
Molecular Formula	C15H15N3O4S
Molecular Weight	333.36 g/mol
Synonyms	Ethyl 8-allyl-5-hydroxy-2-(methylthio)-7-oxo-7,8-dihydro-6H-pyrido[2,3-d]pyrimidine-6-carboxylate; 8-Allyl-5-hydroxy-2-(methylthio)-7-oxo-7,8-dihydro-6H-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester; 6-Carbethoxy-8-allyl-5-hydroxy-2-methylmercapto-7,8-dihydropyrido[2,3-d]pyrimidin-7-one; Pyrido[2,3-d]pyrimidine-6-carboxylic acid derivative; CAS 76360-94-6
EINECS	Contact for details

Quality Control

Our Ethyl 8-Allyl-5-Hydroxy-2-(Methylthio)-7-Oxo-7,8-Dihydropyrido[2,3-D]Pyrimidine-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed under inert atmosphere if specified.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.