Description

Ethyl 8-Allyl-5-Hydroxy-7-Oxo-2-Phenyl-7,8-Dihydropyrido[2,3-D]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrimidine class of heterocyclic compounds. This compound matters as a critical building block in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other therapeutic pathways. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex drug molecules, especially kinase inhibitors.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Organic Synthesis Building Block: Utilized in constructing complex polyheterocyclic systems due to its reactive functional groups (allyl, ester, hydroxy).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Employed in universities and institutes for studying heterocyclic chemistry and developing new synthetic methodologies.
• Chemical Reference Standard: Can be used as a high-purity standard for analytical method development and quality control in API production.

Basic Information

Product Name	Ethyl 8-Allyl-5-Hydroxy-7-Oxo-2-Phenyl-7,8-Dihydropyrido[2,3-D]Pyrimidine-6-Carboxylate
CAS No.	76360-63-9
Molecular Formula	C19H17N3O4
Molecular Weight	351.36 g/mol
Synonyms	Ethyl 8-allyl-5-hydroxy-7-oxo-2-phenyl-7,8-dihydro-5H-pyrido[2,3-d]pyrimidine-6-carboxylate; 8-Allyl-5-hydroxy-7-oxo-2-phenyl-7,8-dihydro-5H-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester; 5H-Pyrido[2,3-d]pyrimidine-6-carboxylic acid, 8-allyl-7,8-dihydro-5-hydroxy-7-oxo-2-phenyl-, ethyl ester; Ethyl 8-allyl-5-hydroxy-7-oxo-2-phenyl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylate; Pyrido[2,3-d]pyrimidine derivative CAS 76360-63-9
EINECS	Contact for details

Quality Control

Our Ethyl 8-Allyl-5-Hydroxy-7-Oxo-2-Phenyl-7,8-Dihydropyrido[2,3-D]Pyrimidine-6-Carboxylate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.