Description

1'n-Benzyl Biotin CAS NO 76335-62-1 is a chemically modified derivative of biotin (Vitamin B7), designed for advanced research and synthesis applications. This compound is valued for its role as a key intermediate and protecting group in the development of novel pharmaceuticals and biochemical probes. It is primarily sought by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for creating targeted biotinylated compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in oncology and metabolic disease research.
• Bioconjugation & Probe Development: Used to create biotin-labeled molecules for diagnostic assays, imaging, and targeted drug delivery systems.
• Biochemical Research: Serves as a protected form of biotin for studying vitamin-mediated processes, enzyme mechanisms, and cellular uptake.
• Peptide Synthesis: Employed in solid-phase peptide synthesis (SPPS) to introduce biotin motifs into peptides and proteins.
• Affinity Chromatography Ligand Precursor: A starting material for synthesizing specialized ligands used in purification columns.
• Nutraceutical R&D: Investigated for the development of advanced nutritional supplements with modified bioavailability.

Basic Information

Product Name	1'n-Benzyl Biotin
CAS No.	76335-62-1
Molecular Formula	C17H24N2O3S
Molecular Weight	336.45 g/mol
Synonyms	N1-Benzylbiotin; 1-N-Benzylbiotin; Biotin N1-Benzyl Ester; (+)-Biotin N1-Benzylamide; D-Biotin N1-Benzyl Derivative; Vitamin H Benzyl Derivative; 5-[(3aS,4S,6aR)-2-Oxo-1-benzyl-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic Acid
EINECS	Contact for details

Quality Control

Our 1'n-Benzyl Biotin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide Certificates of Analysis (COA) with each shipment to ensure full traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.