Description

Methyl 3,5-Diiodo-L-Tyrosinate is a high-purity, iodinated tyrosine derivative that serves as a critical building block in advanced organic synthesis and pharmaceutical research. This compound is valued for its role as a versatile intermediate in the development of novel bioactive molecules, particularly in medicinal chemistry. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of thyroid hormone analogs, radiopharmaceutical precursors, and other specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of thyroid hormone analogs and receptor ligands.
• Radiopharmaceutical Research: Used in the development of iodine-labeled compounds for diagnostic imaging and therapeutic applications.
• Biochemical Research: Serves as a modified amino acid derivative for studying enzyme inhibition and protein interactions.
• Organic Synthesis: A versatile building block for constructing complex molecules in medicinal chemistry programs.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Methyl 3,5-Diiodo-L-Tyrosinate
CAS No.	76318-50-8
Molecular Formula	C10H9I2NO3
Molecular Weight	444.99 g/mol
Synonyms	L-Tyrosine, 3,5-diiodo-, methyl ester; Methyl (2S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoate; 3,5-Diiodo-L-tyrosine methyl ester; Methyl 3,5-diiodotyrosinate; DIITyr-OMe; (S)-Methyl 2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoate
EINECS	Contact for details

Quality Control

Our Methyl 3,5-Diiodo-L-Tyrosinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.