Description

H-Tyr-Gly-Gly-Phe-Met-Arg-Oh Acoh is a heptapeptide derivative, specifically the acetate salt of the peptide sequence Tyr-Gly-Gly-Phe-Met-Arg. This compound is a key intermediate in peptide synthesis and biochemical research, valued for its role in studying opioid receptor interactions and signal transduction pathways. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in neurobiology and analgesic drug discovery.

Application

• Pharmaceutical Research & Development: As a critical intermediate in the synthesis of opioid peptide analogs and related bioactive compounds.
• Biochemical Assays: Used as a reference standard or substrate in enzyme studies and receptor binding assays to investigate opioid system function.
• Neuroscience Research: A tool compound for studying pain modulation, addiction mechanisms, and neuropeptide metabolism in academic and industrial settings.
• Peptide Library Synthesis: Serves as a building block for constructing focused peptide libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Process Development: Employed in the scale-up and optimization of solid-phase or solution-phase peptide synthesis manufacturing processes.

Basic Information

Product Name	H-Tyr-Gly-Gly-Phe-Met-Arg-Oh Acoh
CAS No.	76310-14-0
Molecular Formula	C37H55N11O10S • xC2H4O2
Molecular Weight	853.99 g/mol (Free base, C37H55N11O10S)
Synonyms	Tyr-Gly-Gly-Phe-Met-Arg-OH acetate; H-Tyr-Gly-Gly-Phe-Met-Arg-OH acetate salt; YGGFMR-OH • AcOH; Heptapeptide YGGFMRA acetate; Opioid peptide fragment (6-11) acetate; [Arg6]-Met-Enkephalin acetate; L-Tyrosyl-glycyl-glycyl-L-phenylalanyl-L-methionyl-L-arginine acetate
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch of H-Tyr-Gly-Gly-Phe-Met-Arg-Oh Acoh undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, content, and residual solvent levels are provided to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/IC)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.