Description

Z-Ala-Lys-Oh is a protected dipeptide derivative, specifically the benzyloxycarbonyl (Z) protected form of alanyl-lysine. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), where it is used to introduce the alanyl-lysine sequence while protecting the lysine side chain amine. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who require high-purity, well-defined intermediates for the production of complex peptides, potential therapeutic agents, and biochemical research tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential assembly of longer peptide chains.
• Pharmaceutical Research: Used in the development and synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation: Acts as a spacer or linker molecule in the creation of peptide-protein or peptide-antibody conjugates for diagnostic and therapeutic applications.
• Biochemical Tool Development: Employed in the synthesis of enzyme substrates, inhibitors, and probes for studying protease activity and other biological mechanisms.
• Custom Peptide Services: A fundamental raw material for CROs and CDMOs offering bespoke peptide synthesis services.
• Academic Research: Supports fundamental studies in peptide chemistry, structure-activity relationships (SAR), and medicinal chemistry.

Basic Information

Product Name	Z-Ala-Lys-Oh
CAS No.	76264-07-8
Molecular Formula	C17H25N3O5
Molecular Weight	351.40 g/mol
Synonyms	Nα-Benzyloxycarbonyl-L-alanyl-L-lysine; Z-L-Ala-L-Lys-OH; CBZ-L-Ala-L-Lys-OH; N-CBZ-L-alanyl-L-lysine; Benzyloxycarbonyl-alanyl-lysine; (2S)-2-[[(2S)-2-[[(phenylmethoxy)carbonyl]amino]propanoyl]amino]-6-aminohexanoic acid; Alanyllysine, N2-[(phenylmethoxy)carbonyl]-; Z-Ala-Lys
EINECS	Contact for details

Quality Control

Our Z-Ala-Lys-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and Mass Spectrometry. We provide full traceability and a Certificate of Analysis (COA) with every shipment, detailing assay, chiral purity, and impurity profiles to ensure it meets the stringent requirements for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-L isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.