Description

4-(Benzyloxy)-3-Fluoroaniline Hcl is a high-purity, functionalized aniline derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific fluorinated and benzyl-protected amine functionalities.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in areas targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic amines used in electronic materials for displays and lighting.
• Polymer Modification: Employed to introduce amine functional groups into polymer backbones for specialty resins and high-performance materials.
• Chemical Research & Development: A versatile reagent for academic and industrial research in medicinal chemistry and material science.
• Dye & Pigment Intermediate: Potential use in the synthesis of specialized fluorinated dyes and colorants.

Basic Information

Product Name	4-(Benzyloxy)-3-Fluoroaniline Hydrochloride
CAS No.	76243-25-9
Molecular Formula	C13H13ClFNO
Molecular Weight	253.70 g/mol
Synonyms	3-Fluoro-4-(phenylmethoxy)aniline hydrochloride; 1-(Benzyloxy)-2-fluoro-4-aminobenzene hydrochloride; 4-Amino-2-fluorophenyl benzyl ether hydrochloride; Benzenemethanamine, 4-(phenylmethoxy)-3-fluoro-, hydrochloride; 4-(Benzyloxy)-3-fluoro-benzenamine HCl; 3-Fluoro-4-benzyloxyaniline HCl; 4-Benzyloxy-3-fluoroaniline hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 4-(Benzyloxy)-3-Fluoroaniline Hcl is produced under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and elemental analysis, to ensure compliance with exacting standards for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.