Description

4-Bromo-2-(4-Fluorophenyl)Pyrimidine is a high-value halogenated pyrimidine derivative, a crucial building block in modern synthetic chemistry. Its molecular structure, featuring both bromine and fluorine substituents, makes it an essential intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogenated aromatic system.
• Material Science: Serves as a precursor for organic electronic materials and liquid crystals.
• Chemical Biology: Employed as a probe or labeling agent in biochemical research due to its reactive bromine site.
• Cross-Coupling Reactions: Acts as a versatile substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Library Synthesis: Used in high-throughput and combinatorial chemistry for generating diverse compound libraries for screening.

Basic Information

Product Name	4-Bromo-2-(4-Fluorophenyl)Pyrimidine
CAS No.	76128-73-9
Molecular Formula	C10H6BrFN2
Molecular Weight	253.07 g/mol
Synonyms	2-(4-Fluorophenyl)-4-bromopyrimidine; 4-Bromo-2-(p-fluorophenyl)pyrimidine; 4-Bromo-2-(4-fluorophenyl)-pyrimidine; Pyrimidine, 4-bromo-2-(4-fluorophenyl)-; 76128-73-9; 4-Bromo-2-(4'-fluorophenyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(4-Fluorophenyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.