Description

4-Bromo-2-(3-Fluorophenyl)Pyrimidine is a high-value halogenated pyrimidine derivative, a crucial building block in modern synthetic organic chemistry. Its core value lies in its bifunctional reactivity, where the bromine and pyrimidine nitrogen atoms serve as versatile handles for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials. Its specific structure makes it an ideal intermediate for creating targeted libraries in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for functionalized ligands in catalysis and for creating organic electronic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical studies.
• Custom Synthesis: A fundamental starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	4-Bromo-2-(3-Fluorophenyl)Pyrimidine
CAS No.	76128-72-8
Molecular Formula	C10H6BrFN2
Molecular Weight	253.07 g/mol
Synonyms	2-(3-Fluorophenyl)-4-bromopyrimidine; 4-Bromo-2-(3-fluorophenyl)pyrimidine; 4-Bromo-2-(m-fluorophenyl)pyrimidine; 76128-72-8; Pyrimidine, 4-bromo-2-(3-fluorophenyl)-; 4-Bromo-2-(3-fluorophenyl)-pyrimidine; 4-Bromo-2-(3'-fluorophenyl)pyrimidine
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2-(3-Fluorophenyl)Pyrimidine adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Standard analytical techniques including HPLC, GC, NMR, and mass spectrometry are employed for comprehensive characterization. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles. We support development and commercial projects with material that meets the exacting standards required for pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.