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S-Glucagon Dimer, Trp- CAS NO 75977-14-9
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CAS No.:75977-14-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
S-Glucagon Dimer, Trp- CAS NO 75977-14-9 is a synthetic peptide dimer derivative of glucagon, a key hormone involved in glucose metabolism. This modified form is of significant interest for advanced research and development in metabolic disease studies and peptide-based therapeutic discovery. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies specializing in endocrinology and diabetes research.
Application
- Pharmaceutical Research & Development: Serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel glucagon analogs and peptide therapeutics.
- Metabolic Disease Studies: Used in in vitro and in vivo research to investigate glucose regulation, receptor binding affinity, and signaling pathways related to diabetes and obesity.
- Biochemical Assay Development: Employed as a key component in the development and validation of high-throughput screening (HTS) assays and diagnostic kits targeting glucagon-related pathways.
- Structure-Activity Relationship (SAR) Studies: The dimeric, tryptophan-modified structure makes it a valuable tool for studying peptide stability, aggregation behavior, and the impact of structural modifications on biological activity.
- Academic & Institutional Research: Supports fundamental research in endocrinology, peptide chemistry, and hormone action at universities and government research laboratories.
Basic Information
| Product Name | S-Glucagon Dimer, Trp- |
| CAS No. | 75977-14-9 |
| Molecular Formula | Contact for details |
| Molecular Weight | Contact for details |
| Synonyms | Glucagon Dimer (Tryptophan-modified); S-Glucagon Dimer Tryptophan derivative; Trp-modified Glucagon Dimer; Glucagon Homodimer Analog; [Trp]-Glucagon Dimer; Peptide dimer of glucagon; 75977-14-9; Glucagon-related peptide dimer |
| EINECS | Contact for details |
Quality Control
Our S-Glucagon Dimer, Trp- is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC/MS) | Conforms to reference standard |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 5.0% |
| Peptide Content | ≥ 80% |
| Single Impurity (HPLC) | ≤ 2.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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