Description

Pancreatic Polypeptide, Human is a 36-amino acid peptide hormone produced by the endocrine pancreas. This compound plays a significant role in regulating pancreatic and gastrointestinal secretions, making it a valuable tool for metabolic and endocrine research. It is essential for researchers and developers in the pharmaceutical and biotechnology sectors focused on diabetes, obesity, and digestive disorders.

Application

• Biomedical Research: Used as a critical standard and reagent in studies investigating pancreatic function, appetite regulation, and energy homeostasis.
• Diagnostic Development: Serves as a reference antigen or calibrator in the development of immunoassays (e.g., ELISA, RIA) for measuring pancreatic polypeptide levels in clinical samples.
• Pharmacological Studies: Employed in preclinical research to study receptor binding, signal transduction pathways, and the physiological effects of PP-fold peptides.
• Cell Culture & In Vitro Models: Applied in tissue culture experiments to examine its effects on cell proliferation, secretion, and metabolic activity.
• Peptide Chemistry Reference: Utilized as a high-purity benchmark in analytical method development and peptide synthesis quality control.

Basic Information

Product Name	Pancreatic Polypeptide, Human
CAS No.	75976-10-2
Molecular Formula	C201H315N55O58S
Molecular Weight	4182.6 g/mol
Synonyms	Human Pancreatic Polypeptide; hPP; PPY; Pancreatic Polypeptide (1-36), human; PP; PYY; PP-fold Peptide; NPY; Neuropeptide Y Family Peptide; PPY(1-36); PPY Human
EINECS	Contact for details

Quality Control

Our Pancreatic Polypeptide, Human is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Biological Activity	Assessed by receptor binding assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.