Description

Tuftsin, Arg(3)- is a synthetic, biologically active tetrapeptide analog of the natural immunomodulator tuftsin. This compound is of significant interest for its enhanced stability and potent immunostimulatory properties compared to its native counterpart. It is primarily utilized in advanced biomedical research and pharmaceutical development, particularly in the fields of immunology, oncology, and novel therapeutic agent discovery. The CAS number for this compound is 75929-73-6.

Application

• Immunology Research: Used as a model compound to study macrophage activation, phagocytosis, and the modulation of innate immune responses.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the development of novel immunotherapies and vaccine adjuvants.
• Oncology Studies: Investigated for its potential to enhance anti-tumor activity by stimulating immune cell function against cancer cells.
• Biochemical Reagent: Employed in enzymatic studies and as a standard in analytical methods (e.g., HPLC, MS) for peptide quantification and identification.
• Cell Culture & In Vitro Assays: Applied in cell-based assays to evaluate immune cell proliferation, cytokine production, and signal transduction pathways.
• Preclinical Formulation: Used in the development of drug delivery systems, including liposomal and nanoparticle formulations targeting immune cells.

Basic Information

Product Name	Tuftsin, Arg(3)-
CAS No.	75929-73-6
Molecular Formula	C₂₃H₄₀N₁₀O₆
Molecular Weight	552.63 g/mol
Synonyms	L-Threonyl-L-lysyl-L-prolyl-L-arginine; Arg(3)-Tuftsin; [Arg3]-Tuftsin; Tuftsin (Arg-3) analog; Immunostimulant peptide TKPR; Thr-Lys-Pro-Arg; H-Thr-Lys-Pro-Arg-OH
EINECS	Contact for details

Quality Control

Our Tuftsin, Arg(3)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide Certificates of Analysis (COA) detailing all specifications, ensuring traceability and compliance with research-grade standards. Custom synthesis and purity grades (e.g., >95%, >98%, >99%) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Conforms to theoretical values
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, dimethyl sulfoxide (DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.