Description

4-Bromo-2,3,5,6-Tetrafluorobenzylalcohol is a high-value fluorinated aromatic building block, distinguished by its unique combination of bromine and fluorine substituents on a benzyl alcohol core. This structure makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where electronic and steric properties must be precisely tuned. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop novel compounds with enhanced bioactivity and stability.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where fluorine atoms improve metabolic stability and membrane permeability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, enhancing charge transport and thermal stability.
• Polymer Modification: Incorporates into specialty polymers to impart unique solubility, chemical resistance, and low surface energy properties.
• Cross-Coupling Reactions: The bromine substituent acts as a handle for versatile palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) for complex molecule assembly.
• Ligand & Catalyst Development: Utilized in the synthesis of sophisticated fluorinated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Bromo-2,3,5,6-Tetrafluorobenzylalcohol
CAS No.	75865-45-1
Molecular Formula	C7H3BrF4O
Molecular Weight	258.99 g/mol
Synonyms	(4-Bromo-2,3,5,6-tetrafluorophenyl)methanol; 2,3,5,6-Tetrafluoro-4-bromobenzyl Alcohol; α-Hydroxymethyl-2,3,5,6-tetrafluoro-4-bromobenzene; 4-Bromo-2,3,5,6-tetrafluorobenzyl Alcohol; 4-Bromo-α,α,α,α-tetrafluorobenzyl Alcohol; 75865-45-1; Perfluorobenzyl Alcohol, 4-Bromo-
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2,3,5,6-Tetrafluorobenzylalcohol is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards, and comprehensive analytical data including HPLC purity, NMR, and GC-MS are documented. A Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and specification adherence for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.