Description

Lhrh, Ac-Dehydro-Phe(1)-Dehydro-4-Cl-Phe(2)-Dehydro-Trp(3,6)- is a synthetic, modified peptide analog of Luteinizing Hormone-Releasing Hormone (LHRH). This compound is engineered with specific dehydro-amino acid substitutions to enhance its stability and biological activity profile. It is primarily utilized in advanced pharmaceutical research and development, particularly in the study of hormone-dependent systems. The CAS number for this substance is 75851-13-7.

Application

• Pharmaceutical Research: Serves as a key reference standard and active ingredient in the development of novel therapeutic agents targeting hormone receptors.
• Endocrinology Studies: Used in biochemical and pharmacological research to investigate the modulation of the hypothalamic-pituitary-gonadal axis.
• Peptide Chemistry Development: Acts as a model compound for studying the structure-activity relationships (SAR) of modified peptide hormones.
• Preclinical & Clinical Trials: Employed in the formulation and testing of potential treatments for conditions such as hormone-dependent cancers and reproductive disorders.
• Bioconjugation & Labeling: Provides a scaffold for the development of diagnostic probes and targeted drug delivery systems due to its specific receptor affinity.

Basic Information

Product Name	Lhrh, Ac-Dehydro-Phe(1)-Dehydro-4-Cl-Phe(2)-Dehydro-Trp(3,6)-
CAS No.	75851-13-7
Molecular Formula	C64H78ClN15O12
Molecular Weight	1268.83 g/mol
Synonyms	Ac-D-δPhe1-δpCl-D-Phe2-D-Trp3,6-LHRH; [Ac-δPhe1, δpCl-D-Phe2, D-Trp3,6]-LHRH; Modified LHRH Antagonist; Luteinizing Hormone-Releasing Hormone Analog; Gonadotropin-Releasing Hormone (GnRH) Antagonist Analog; Peptide LHRH Antagonist; 75851-13-7
EINECS	Contact for details

Quality Control

Our Lhrh, Ac-Dehydro-Phe(1)-Dehydro-4-Cl-Phe(2)-Dehydro-Trp(3,6)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetic Acid Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.