Description

3-Hydroxy-7-Oxocholanoyltaurine is a conjugated bile acid derivative, specifically a taurine conjugate of a hydroxylated oxo-bile acid. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a potential intermediate or reference standard in the study of bile acid metabolism and signaling pathways. It is primarily utilized by research institutions and pharmaceutical development companies focused on metabolic disorders, liver function, and novel therapeutic agent synthesis.

Application

• Pharmaceutical Research Intermediate: Serves as a key synthetic intermediate or building block in the development of new therapeutic agents targeting metabolic pathways.
• Biochemical Reference Standard: Used as a high-purity analytical standard for the identification and quantification of bile acid derivatives in complex biological matrices via HPLC or LC-MS.
• Metabolic Pathway Studies: Employed in in-vitro and in-vivo research to investigate bile acid synthesis, conjugation, and their role in lipid digestion and cholesterol homeostasis.
• Cell Signaling Research: Applied in studies exploring the function of bile acids as signaling molecules and their interactions with receptors like FXR (Farnesoid X Receptor).
• Diagnostic Reagent Development: Acts as a critical component in the formulation of calibration kits and assays for clinical diagnostics related to liver and gastrointestinal health.

Basic Information

Product Name	3-Hydroxy-7-Oxocholanoyltaurine
CAS No.	75808-01-4
Molecular Formula	C₂₆H₄₃NO₇S
Molecular Weight	513.69 g/mol
Synonyms	7-Oxo-3α-hydroxy-5β-cholan-24-oyltaurine; Tauro-7-oxo-3α-hydroxy-5β-cholanic acid; 3α-Hydroxy-7-oxo-5β-cholan-24-oyltaurine; 7-Ketolithocholyltaurine; Taurine conjugate of 7-ketolithocholic acid; 3α-Hydroxy-7-oxocholanoyltaurine; N-(3α-Hydroxy-7-oxo-5β-cholan-24-oyl)taurine
EINECS	Contact for details

Quality Control

We supply 3-Hydroxy-7-Oxocholanoyltaurine in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. For specific pharmacopeial standards (e.g., USP, EP) or custom purity requirements, please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.