Description

Acetyl-Alanyl-Alanyl-Tyrosine CAS NO 75795-03-8 is a synthetic tripeptide derivative, specifically an acetylated form of the alanyl-alanyl-tyrosine sequence. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a model substrate for studying enzyme kinetics, particularly for proteases like chymotrypsin. It serves as a critical building block and intermediate for peptide synthesis, enabling the development of novel therapeutic agents and research tools. Key industries that utilize this high-purity peptide include pharmaceutical R&D, biotechnology, and academic research institutions focused on enzymology and peptide chemistry.

Application

• Enzyme Substrate: Used as a specific chromogenic or fluorogenic substrate for studying the activity and inhibition of serine proteases, including chymotrypsin and subtilisin.
• Pharmaceutical Intermediate: Serves as a key synthetic building block in the research and development of novel peptide-based drugs and bioactive compounds.
• Biochemical Research: Employed in enzymology studies to investigate peptide bond cleavage mechanisms, enzyme specificity, and kinetic parameters.
• Reference Standard: Utilized as a high-purity analytical standard in HPLC and LC-MS methods for quality control and method validation in peptide analysis.
• Peptide Library Synthesis: Acts as a core structure or component in the combinatorial synthesis of peptide libraries for drug discovery screening.
• Cell Biology Studies: Applied in research exploring peptide transport, cellular uptake mechanisms, and intracellular signaling pathways.

Basic Information

Item	Details
Product Name	Acetyl-Alanyl-Alanyl-Tyrosine
CAS No.	75795-03-8
Molecular Formula	C₁₉H₂₆N₄O₆
Molecular Weight	406.43 g/mol
Synonyms	Ac-AAY-OH; N-Acetyl-L-alanyl-L-alanyl-L-tyrosine; Acetyl-Ala-Ala-Tyr; AAY; N-Acetyl-AAY; L-Tyrosine, N-acetyl-L-alanyl-L-alanyl-; Ac-Ala-Ala-Tyr-OH; N-Acetylalanylalanyltyrosine
EINECS	Contact for details

Quality Control

Our Acetyl-Alanyl-Alanyl-Tyrosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Assay	95.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.