Description

4-Keto-L-Proline Hydrobromide is a high-purity, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a versatile chiral building block and a key precursor for the synthesis of complex molecules, including proline analogs and peptidomimetics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide-based therapeutics, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of proline-containing drugs and novel API candidates.
• Peptide Chemistry: Used in the research and development of modified peptides and peptidomimetics to enhance stability and biological activity.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to proline metabolism and processing.
• Asymmetric Synthesis: Employed as a starting material or catalyst component in stereoselective organic reactions.
• Fine Chemical Production: A key raw material for manufacturing high-value specialty chemicals and custom synthesis projects.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	4-Keto-L-Proline Hydrobromide
CAS No.	75776-67-9
Molecular Formula	C5H7NO3·HBr
Molecular Weight	210.03 g/mol
Synonyms	(S)-4-Oxopyrrolidine-2-carboxylic acid hydrobromide; L-4-Ketoproline HBr; 4-Oxo-L-proline hydrobromide; (2S)-4-Oxopyrrolidine-2-carboxylic acid hydrobromide; 4-Keto-L-proline HBr; 4-Oxoproline hydrobromide; L-Pyroglutamic acid hydrobromide (related derivative)
EINECS	Contact for details

Quality Control

Our 4-Keto-L-Proline Hydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed results from HPLC, NMR, and other relevant analytical techniques. Our quality commitment aligns with the standards expected for pharmaceutical research and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed and stored under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.