Description

β-D-Glucopyranosiduronic Acid, (3α,5β,7β)-7-Hydroxy-24-Oxo-24-[(2-Sulfoethyl)Amino]Cholan-3-Yl, Dipotassium Salt (9Ci) is a high-purity, specialized bile acid derivative conjugated with a glucuronic acid moiety. This compound is of significant value in pharmaceutical research and development, particularly for studying metabolic pathways, drug conjugation, and as a reference standard. It is primarily sought by research institutions and pharmaceutical companies engaged in advanced hepatobiliary and detoxification studies, as well as in the synthesis of novel diagnostic agents.

Application

• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for quality control and method validation in drug development.
• Metabolic Pathway Research: Critical for in vitro and in vivo studies of bile acid metabolism, glucuronidation processes, and liver function.
• Biochemical Reagent: Employed in enzymatic assays and as a substrate or inhibitor for studying sulfotransferase and glucuronosyltransferase enzymes.
• Drug Conjugation Studies: Serves as a model compound for investigating the pharmacokinetics and detoxification pathways of drug metabolites.
• Diagnostic Agent Development: Potential use in the research and synthesis of targeted contrast agents or biomarkers for hepatobiliary imaging.
• Academic Research: Utilized in university and institutional labs for fundamental research in biochemistry, medicinal chemistry, and toxicology.

Basic Information

Item	Details
Product Name	β-D-Glucopyranosiduronic Acid, (3α,5β,7β)-7-Hydroxy-24-Oxo-24-[(2-Sulfoethyl)Amino]Cholan-3-Yl, Dipotassium Salt (9Ci)
CAS No.	75672-32-1
Molecular Formula	C32H51K2NO13S
Molecular Weight	767.99 g/mol
Synonyms	7-Hydroxy-24-oxo-24-[(2-sulfoethyl)amino]cholan-3-yl β-D-glucopyranosiduronic acid dipotassium salt; Tauro-7α-hydroxy-3-oxochol-24-oyl glycine β-D-glucuronide dipotassium salt (related analog); Bile acid glucuronide derivative; Cholan-24-amide, N-(2-sulfoethyl)-7-hydroxy-3-(β-D-glucopyranuronosyl)oxy]-, potassium salt (1:2); Research compound 75672-32-1; Potassium 7α-hydroxy-3β-[(β-D-glucopyranuronosyl)oxy]-24-oxo-24-[(2-sulfoethyl)amino]cholanate
EINECS	Contact for details

Quality Control

Our β-D-Glucopyranosiduronic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets exacting standards for research use. Certificates of Analysis (COA) with detailed chromatographic data and batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to maintain stability and purity. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Assay	90.0% - 110.0% (on anhydrous basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.