Description

Benzo(B)Pyrrolo(3,2,1-Jk)(1,4)Benzodiazepine, 1,2,6,7-Tetrahydro-7-((D Imethylamino)Acetyl)-6-(2-Phenylethyl)-, Ethanedioate (1:1) is a high-purity, complex heterocyclic compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or active pharmaceutical ingredient (API) precursor for the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new drug candidates, particularly within the central nervous system (CNS) and oncology spaces.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel benzodiazepine-derived active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Preclinical Studies: Serves as a reference standard or test compound in pharmacological and toxicological evaluations.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for complex, high-value specialty chemicals.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Item	Details
Product Name	Benzo(B)Pyrrolo(3,2,1-Jk)(1,4)Benzodiazepine, 1,2,6,7-Tetrahydro-7-((D Imethylamino)Acetyl)-6-(2-Phenylethyl)-, Ethanedioate (1:1)
CAS No.	75643-16-2
Molecular Formula	C25H27N3O5
Molecular Weight	449.50 g/mol
Synonyms	7-[(Dimethylamino)acetyl]-6-(2-phenylethyl)-1,2,6,7-tetrahydrobenzo[b]pyrrolo[3,2,1-jk][1,4]benzodiazepine ethanedioate; 6-(2-Phenylethyl)-7-[(dimethylamino)acetyl]-1,2,6,7-tetrahydrobenzo[b]pyrrolo[3,2,1-jk][1,4]benzodiazepine oxalate; Oxalate salt of a benzodiazepine derivative; Pyrrolobenzodiazepine oxalate salt; PBD-oxalate intermediate; CAS 75643-16-2
EINECS	Contact for details

Quality Control

Our production of Benzo(B)Pyrrolo(3,2,1-Jk)(1,4)Benzodiazepine, 1,2,6,7-Tetrahydro-7-((D Imethylamino)Acetyl)-6-(2-Phenylethyl)-, Ethanedioate (1:1) adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.